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At this point, I suspect it will surprise no-one who follows the field to learn that the accumulation of senescent cells is a significant cause of degenerative disc disease. The evidence from a mouse study that is provided in the open access paper here doesn’t quite rise to establishing that claim, but it is compelling…

Researchers here process the enormous set of health data found in the UK Biobank to conclude that there is comparatively little sign of cognitive decline in cohorts younger than age 65. After that, loss of function sets in quite rapidly, however. This is good news for those of us taking good care of our health,…

IMAGE: Stand Up To Cancer logo. view more  Credit: Stand Up To Cancer (Los Angeles- March 25, 2019) – Stand Up To Cancer (SU2C) today announced the recipient of its inaugural Stand Up To Cancer Peggy Prescott Early Career Scientist Award in Colorectal Cancer Research, which was funded by Dallas Cowboys QB and SU2C Ambassador Dak…

Billions worldwide are infected with tropical worms. Unsurprisingly, most of these people live in poor countries, kept poor by the effects of worm-related malnourishment. What may surprise many is that worms also cause the majority of cases of some cancers in these countries. Published in Frontiers in Medicine as a special article collection on parasite-associated…

GPs will have a pivotal role in ensuring the success of the new Faster Diagnosis Standard (FDS) for Cancer, new research from the University of Surrey finds. In the first study of its kind, published today in the British Journal of General Practice and funded by Cancer Research UK, researchers investigated public attitudes towards the…

IMAGE: Ramón Muñoz-Chápuli and Rita Carmona, researchers of the UMA Department of Animal Biology, have identified a new molecular mechanism involved in pancreas repair. These experts have demonstrated that Wt1 gene deletion… view more  Credit: University of Malaga Furthermore, they have verified that, after a pancreatic damage, Wt1 gene becomes activated in the so-called stellate cells…

IMAGE: This is Jennifer Wargo, M.D. view more  Credit: MD Anderson Cancer Center White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. Study results will be…

(Boston)–Researchers have identified a biomarker and a possible new therapy for melanoma. Microphthalmia-associated transcription factor (MITF) is a protein that plays a pivotal role in the maintenance of the melanocyte (cells that make melanin) lineage, differentiation of normal and malignant melanocytes and the survival of melanoma cells. “We have now detected the first useful chemical…

More than a decade of research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs. Published this week in the journal Proceedings of the National Academy of Sciences, the findings could potentially have…

IMAGE: Thierry Pécot, Ph.D., researcher at the Medical University of South Carolina, works in his laboratory at the Hollings Cancer Center. view more  Credit: MUSC Hollings Cancer Center, Emma Vought The Chan Zuckerberg Initiative (CZI) announced $17 million in funding and its selection of 17 CZI Imaging Scientists — engineers, physicists, mathematicians, computer scientists, and biologists…

A new study reveals that preventive medications–such as those to lower blood pressure or cholesterol, or to protect bone health, among others–are commonly prescribed during the last year of life of older adults with cancer, even though they are unlikely to provide meaningful benefits. Published early online in CANCER, a peer-reviewed journal of the American…

IMAGE: This image depicts how thousands of genes organize into a network in a cell. view more  view more  Credit: Raamesh Deshpande When the Human Genome Project was completed, in 2003, it opened the door to a radical new idea of health – that of personalized medicine, in which disease risk and appropriate treatment would be…

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