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The adaptive immune system consists of many different types of cell, undertaking many different tasks, all falling into the two broad categories of T cells and B cells. With age, the immune system falls into a chronic state of inflammation and overactivation (inflammaging) at the same time as it becomes ever less capable of defending…

20 Mar 2019 20 Mar 2019 Light Physical Activity Correlates with Reduced Risk of Cardiovascular Disease Loading… Loading… One of the more interesting findings in the epidemiology of exercise, enabled by the development of lightweight accelerometers to measure daily activity, is that even very modest levels of movement and exertion have a significant correlation with…

Previous studies have revealed a link between hot tea drinking and risk of esophageal cancer, but until now, no study has examined this association using prospectively and objectively measured tea drinking temperature. A new International Journal of Cancer study achieved this by following 50,045 individuals aged 40 to 75 years for a median of 10…

Combining medications that suppress the immune system has been successful in treating young patients with Crohn’s disease, but some physicians have been reluctant to use this strategy in older patients because of concerns about safety. Now an Alimentary Pharmacology & Therapeutics study indicates that older patients can be safely and effectively treated with such combined…

Turn.bio is Gary Hudson’s latest company, now that others are running the day to day development at Oisin Biotechnologies. The Turn.bio staff are working on a particular take on the idea of inducing pluripotence in cells in vivo as a form of compensatory therapy for aging. This is a concept that struck me as being…

19 Mar 2019 19 Mar 2019 Chronic Periodontitis Only Modestly Raises the Risk of Dementia Loading… Loading… Periodontitis is the later stage of gum disease, an inflammatory condition largely caused by particular strains of bacteria found in the mouth. While there is a fair amount of promising work related to destroying or sabotaging the disease-causing…

The Academy for Health and Lifespan Research was recently announced, an initiative analogous to that of the long-running Longevity Dividend group, but hopefully more energetic and more focused on at least some rejuvenation biotechnologies such as senolytic therapies. The principals include many of the researchers now involved in startup biotech companies working on ways to…

Paper: Serious Adverse Events in African American Cancer Patients with Sickle Cell Trait and Inherited Hemoglobinopathies in a SEER-Medicare Claims CohortCorresponding author: Dr Helen SwedeContact: [email protected] Author summary: African-American cancer patients die at higher rates than white patients despite recent longevity increases for patients in all race/ethnic groups. Some studies have shown African-Americans have worse…

A new method of determining the sequence of molecules in DNA can be used to detect small fragments of cancerous genetic material in blood samples from lung cancer patients with a high degree of accuracy, according to new research published in the leading cancer journal Annals of Oncology [1] today (Wednesday). Results from analyses of…

IMAGE: Dr. Ajith Karunarathne, assistant professor in The University of Toledo Department of Chemistry and Biochemistry view more  view more  While investigating why cholesterol-lowering drugs called statins cause negative side effects such as blurred vision, short-term memory loss or increased risk for diabetes, cellular chemists at The University of Toledo discovered several previously unknown benefits. It…

IMAGE: Loss of EZH2 accelerates the formation of leukemic cells in the bone marrow of mice expressing the oncogenic fusion protein AML1-ETO9a. view more  Credit: Basheer et al., 2019 British researchers have discovered that an epigenetic protein called EZH2 delays the development of acute myeloid leukemia (AML) but then switches sides once the disease is established…

IMAGE: Images in a 63-year-old asymptomatic woman who was recalled because a new 8-mm mass was detected in the left breast at screening mam¬mography. (a) Left mediolateral oblique and (b) left… view more  Credit: Radiological Society of North America OAK BROOK, Ill. – The use of digital breast tomosynthesis (DBT), also known as 3-D mammography, may…

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