IMAGE: “We observed a 45 percent decrease in tumor load, ” explains Muriel Cuendet, Associate Professor in the School of Pharmaceutical Sciences of the UNIGE Faculty of Science. view more
Lung cancer is the deadliest form of cancer in the world, and 80% of death are related to smoking. In addition to tobacco control, effective chemoprevention strategies are therefore needed. A team of scientists from the University of Geneva (UNIGE), Switzerland, studied a well-known natural product, resveratrol, which is found in grapes and in red wine. While its chemopreventive properties against cancers affecting the digestive tract have been documented by previous studies, resveratrol has so far shown no effect on lung cancers. Thanks to nasal administration, the UNIGE team obtained very promising results in a study conducted in mice and described in the journal Scientific Reports.
«We tried to prevent lung cancer induced by a carcinogen found in cigarette smoke by using resveratrol, an already well-documented molecule, in a mouse model,» explains Muriel Cuendet, Associate Professor in the School of pharmaceutical sciences of the UNIGE Faculty of Science. This 26 week long study contained four groups of mice. The first one, the control, received neither carcinogen
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