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11

Apr

2018

11

Apr

2018

All Current Assessment Methods for Frailty Correlate with Future Mortality

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Researchers here report on the effectiveness of methods used by researchers and clinicians to assess degree of frailty in older patients. They find that all methods correlate with future mortality, but there are variances in the details of how they correlate to the risk of suffering specific age-related conditions. An optimist might take this to mean that any future rejuvenation therapy with sizable, reliable effects could be correctly categorized as a real rejuvenation therapy by applying the existing systems of testing and assessment. New biomarkers of aging would help, but they are not necessarily required. We’ll find out whether or not this is the case over the next five to ten years as senolytic therapies work their way into widespread use, and the large assessment studies begin.

Frailty is common in elderly people with cardiovascular disease and goes along with elevated mortality. However, no consensus exists on the definition of frailty. Many scores have been developed to assess frailty and to make predictions on disease and mortality, but there is no gold standard. Researchers examined the predictive ability of 35 frailty scores

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Article originally posted at
www.fightaging.org

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