May 30, 2018, NEW YORK — The American Society of Clinical Oncology (ASCO) will honor two Ludwig scientists at its 2018 Annual Meeting in Chicago, Ill., June 1-5, 2018. Ludwig Chicago Co-Director Ralph Weichselbaum will receive the 2018 David A. Karnofsky Memorial Award and Lecture in recognition of his outstanding contributions to cancer research, diagnosis and treatment. ASCO will also recognize Jedd Wolchok, associate director of the Ludwig Center at Memorial Sloan Kettering, as a 2018 Fellow of the American Society of Clinical Oncology (FASCO) for his extraordinary volunteer service, dedication and commitment to ASCO.
Presented annually since 1970, the David A. Karnofsky Memorial Award and Lecture is one of the Society’s highest honors. Ralph Weichselbaum will be recognized for his discoveries in basic mechanisms of signal transduction and gene expression following radiation exposure that led to translational investigations of radio-inducible gene therapy and the integration of chemotherapy and radiotherapy. Weichselbaum, along with Ludwig Board member Samuel Hellman, also proposed the spectrum theory of metastasis, predicting that some patients will develop only limited metastatic disease and that malignancies–which they called oligometastasis–could be cured with targeted radiation or surgery. They recently confirmed this oligometastasis hypothesis with a molecular analysis of
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