Today, the effective treatment of aging can only proceed rapidly as an engineering project. The fine details of the way in which aging progresses at the level of cells and proteins are far from fully understood – but that is not a roadblock to progress. The research community knows enough of the causes of aging to repair them and observe the results. In fact the repair approach, where it has been tried, and as typified by senolytic development to clear senescent cells, is doing far more, with far less expenditure, and in far less time, than other strategies that involve mapping and adjusting the extreme complexity of cellular metabolism.
A good analogy for this situation is that sizable bridges and other large structures were constructed on an empirical basis for millennia prior to a full understanding of materials science, prior to the implementation of computational modeling in architecture. In exactly the same way it is possible to make meaningful progress in the treatment of aging today, and because aging causes far more harm than any other aspect of the human condition, it is our ethical imperative to make that
Article originally posted at