Brain changes responsible for the appetite effects of cannabis identified in animal studies
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New research on how cannabis use alters eating behavior could lead to treatments for appetite loss in chronic illness, according to experts at Washington State University. Using a new procedure to dose lab rats with cannabis vapor, the researchers found how the drug triggers hunger hormones. They also identified specific brain regions that shift to ‘hungry’ mode while under the influence, according to a report they shared this week at the Society for the Study of Ingestive Behavior, an international meeting of scientific experts on eating.

“We all know cannabis use affects appetite, but until recently we’ve actually understood very little about how or why,” explained Jon Davis, Ph.D., researcher in the Department of Integrative Physiology and Neurosciences at Washington State. “By studying exposure to cannabis plant matter, the most widely consumed form, we’re finding genetic and physiological events in the body that allow cannabis to turn eating behavior on or off.”

A recent wave of cannabis legalization for both medical and recreational purposes has stimulated research on its therapeutic potential. A family of compounds called cannabinoids, particularly delta-9 tetrahydrocannabinol (THC), are responsible for its psychological effects. The ability of THC to stimulate appetite is valuable since many illnesses

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