Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn’t work when it comes to…

IMAGE: Environmental Chemist Heather led a three-year study of in-home exposures to semi-volatile organic compounds (SVOCs) among 203 children from 190 families. view more  Credit: Duke Photo DURHAM, N.C. — Children living in homes with all vinyl flooring or flame-retardant chemicals in the sofa have significantly higher concentrations of potentially harmful semi-volatile organic compounds (SVOCs) in…

To my mind far too much effort is expended on trying to figure out the epidemiology of the tiny fraction of humans who manage to live a fair way past one hundred years of age. For one, there just aren’t enough of them to generate truly robust data from which conclusions can be drawn. People…

Funding is pouring into the commercial development of the first rejuvenation therapies, largely meaning senolytic treatments at the present time, alongside various ways of upregulating beneficial stress responses in order to modestly slow aging. As this progresses, we will see an accompanying growth in advocacy for the treatment of aging as a medical condition. The…

Since ketosis is argued to be a component of the effects of calorie restriction, responsible in some part for the reliable benefits to health and longevity that result, some research groups have investigated ways to induce ketosis via treatment rather than via diet. This is a subset of broader efforts to produce calorie restriction mimetic…

IMAGE: Esma Yolcu, Ph.D. view more  view more  Credit: University of Louisville LOUISVILLE, Ky. – A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself. The recombinant protein molecule SA-4-1BBL has been…

IMAGE: This photo shows from left to right Dr. Shalin Naik, Professor Jane Visvader, Dr. Tom Weber and Dr. Delphine Merino. view more  Credit: Walter and Eliza Hall Institute of Medical Research A cutting-edge technique called cellular barcoding has been used to tag, track and pinpoint cells responsible for the spread of breast cancer from the…

The artificial intelligence software, created by researchers at Imperial College London and the University of Melbourne, has been able to predict the prognosis of patients with ovarian cancer more accurately than current methods. It can also predict what treatment would be most effective for patients following diagnosis. The trial, published in Nature Communications took place…

VIDEO: This movie depicts the conformational changes that accompany SUMO E1 binding to COH000. Selected structural elements are labeled and regions of the enzyme that become disordered in the SUMO… view more  view more  Credit: Medical University of South Carolina, courtesy of Dr. Shaun Olsen A research team at the Medical University of South Carolina (MUSC)…

Results from the NRG Oncology clinical study NRG-RTOG 0415 determined that a hypofractionated radiotherapy schedule (H-RT), a treatment schedule that delivers a total dose of radiotherapy over a shorter period of time, is not worse than the conventional radiotherapy schedule (C-RT) in terms of bowel, bladder, sexual, and general quality of life (QOL) as well…

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