(WASHINGTON, April 18, 2018) — Adolescents and young adults with acute leukemia have a survival advantage if they receive treatment at a pediatric cancer center versus an adult center, according to a new study.
The study, published online today in Blood Advances, a journal of the American Society of Hematology, also suggests that treatment at a center affiliated with the National Cancer Institute (NCI) improves overall survival.
Background: Evidence suggests that adolescents and young adults (AYA) with acute lymphocytic leukemia (ALL) fare better when treated with pediatric protocols, which are not uniformly used in adult cancer centers. This study was designed to provide a real-world understanding of the location of care and front-line regimens administered to newly diagnosed AYAs with ALL.
Study methods: Researchers reviewed California Cancer Registry data from 2004-2014 and identified 1,473 newly diagnosed ALL patients ages 15-39. They then designated the patients’ center of care as either pediatric or adult, noting whether the facility was affiliated with the NCI, and assessed overall survival based on treatment setting.
Results: 475 of 1,473 (32%) AYA patients with ALL received care in a pediatric setting; 422 (89%) of these patients received front-line ALL therapy at NCI-designated cancer centers. Among
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