New research uncovers 'stability protein' for cancer treatment
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Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterised a new protein that is important to the genetic stability of our cells. It may be significant for the development of new drugs against genetically determined diseases like cancer, sterility and premature ageing.

All of our cells contain genetic material, DNA, which controls the activity of the cells. If the genetic material is damaged, cancer cells may develop. Therefore, many proteins and enzymes are responsible for stabilising and protecting our DNA against permanent damage and mutations.

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences, University of Copenhagen, have discovered and characterised a new protein called ZUFSP. There is much indication that the protein plays a key role in ensuring that our genetic material remains stable.

‘The protein ZUFSP had not been characterised before, but appeared to contain certain sequences often found in proteins involved in what is referred to as DNA damage response. In addition, there is much indication that ZUFSP plays a main role in helping the cells maintain genetic stability. If we remove ZUFSP, the cells become

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