PSMA PET/CT visualizes prostate cancer recurrence early, impacts radiation therapy
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VIDEO: Jeremie Calais, MD, and Nicholas G. Nickols, MD, PhD, at UCLA explain their research, pointing out that visualizing sites of prostate cancer recurrence accurately and early enough to… view more 

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Credit: UCLA, Los Angeles Calf.

RESTON, Va. – A nuclear medicine scan may locate prostate cancer recurrence after radical prostatectomy early after disease recurrence and could help guide salvage radiotherapy, according to new research from the University of California Los Angeles (UCLA). The study, which utilizes PET/CT with gallium-68 prostate-specific membrane antigen (68Ga-PSMA-11), is documented in the featured article in the February issue of The Journal of Nuclear Medicine.

Prostate cancer biochemical recurrence occurs in 20 to 80 percent of patients within 10 years after radical prostatectomy and is difficult to treat. Salvage radiotherapy is the main option for treatment, but the imaging modalities currently used are not sensitive enough to identify the location of recurrence until it is too late, leading to a “best-guess” approach for targeting the radiotherapy.

“Based on European data, we believe that PSMA PET/CT, an imaging technique that is not yet approved by the U.S. Food and Drug Administration, is sufficiently sensitive to detect and localize the recurrent prostate cancer early enough to potentially guide

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