What we eat plays a significant role in our health. The Experimental Biology 2018 meeting (EB 2018) will showcase new research into how diet could be used to fight cancer and how specific eating patterns can encourage weight loss.
Time-restricted eating reduces tumor growth in mice
Obesity is known to increase the risk for breast cancer, particularly in postmenopausal women. With a long-term goal of developing practical strategies to curb breast cancer risk, researchers from the University of California, in San Diego, examined how restricting eating to a certain number of hours each day might affect cancer. For the study, obese mice modeling the postmenopausal life stage were either given access to high-fat food 24 hours a day or restricted to eating the high-fat food during 8 active hours, simulating daytime eating in people. After 3 weeks, the mice were injected with breast cancer cells. Although the overall quantity of food consumed differed little between the two groups, the time-restricted eating group showed reduced tumor growth as well as better glucose tolerance and insulin resistance, which are both linked to blood sugar control. Additional experiments showed that tumor growth was insulin-dependent, suggesting that time-restricted feeding may act by lowering
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