In a new study based on mouse cells internationally leading protein researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.
Protein researchers from the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen have used mass spectrometry based proteomics to uncover a number of proteins which could play a critical role propagating signals within cells that can lead to uncontrolled cell growth – one of the hallmarks of cancer.
The study, which has been published in the internationally acclaimed scientific journal Cell Reports, was conducted using mouse fibroblast cells.
The researchers behind the study believe the results may prove important to the development of new so-called tyrosine phosphatase-inhibiting drugs for patients suffering from different types cancer – for example Leukaemia – as well as other types of diseases such as Noonan syndrome.
Globally, cancer is one of the leading causes of death according to the World Health Organization. In Denmark one in every three Danes develops cancer at some point in their lives, according to statistics from the Danish Cancer Society.
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