IMAGE: This photo shows haploid human embryonic stem cells created at the Hebrew University’s Azrieli Center for Stem Cells and Genetic Research. view more
Credit: Azrieli Center for Stem Cells and Genetic Research, Hebrew University of Jerusalem
Scientists from the Hebrew University of Jerusalem have generated an atlas of the human genome using a state-of-the-art gene editing technology and human embryonic stem cells, illuminating the roles that our genes play in health and disease. The scientists have reported their findings in the journal Nature Cell Biology.
Embryonic stem cells are a unique resource as they can turn into any adult cell in our bodies. Their versatile nature puts them at the center of attention in the fields of regenerative medicine, disease modeling and drug discovery. In parallel to the discovery of human embryonic stem cells, another milestone in biology was completed with the sequencing of the human genome, and the identification of the entire set of genes responsible for our genetic identity. This finding has led to a new challenge of understanding the function of the genes in the human genome. Now, the new study by scientists at the Hebrew University provides a novel tool to map the function
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