Surgery soon after clinical staging of non-small cell lung cancer reduces cancer progression and improves likelihood of cure

IMAGE: Results showed overall survival improves with accurate staging in clinical stage I NSCLC. view more 

Credit: Harmik J. Soukiasian, M.D.

SAN DIEGO – April 30, 2018 – Significant upstaging or reclassification to a more advanced stage due to cancer progression in non-small cell lung cancer (NSCLC) can occur with each successive week from initial clinical staging to surgery, according to data presented at the American Association for Thoracic Surgery’s 98th Annual Meeting. The same study showed that early intervention after completion of clinical staging leads to increased survival rates.

Clinical staging describes the severity of a patient’s cancer based on the magnitude of the primary tumor and the extent to which this cancer has spread. National Cancer Comprehensive Network (NCCN) Guidelines recommend surgery within eight weeks of completed clinical staging for NSCLC. Surgery offers a chance for cure in the approximately 15 percent of patients who are diagnosed with stage I NSCLC, but effective treatment requires accurate staging to guide effective management. Delay in surgery in clinical stage I is associated with increased upstaging and decreased survival.

“Our study evaluated the possibility of cancer upstaging using a more granular analysis, looking at the rates of upstaging for each


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