For the most part, we know how to mitigate the chronic diseases that plague people in their older years–eat healthily from early on, and get plenty of exercise. But this knowledge hasn’t translated into better health for society at large, and medical systems all around the world are straining increasingly under the weight of aging…

Here’s our handpicked selection of the best interviews, blog posts, popular articles, and breaking biotech news of the last two weeks: Want a systematic overview of every organization chipping away at human aging right now? Then you’ll love this nearly 800-page report from the Biogerontology Research Foundation. Put it in your queue for bedtime reading….

Here’s an interesting experiment that I don’t recommend trying at home. Take a strain of mice, and choose what age you’d like them to live to. The average lifespan for mice in captivity is around two years, so let’s say you give them six months. Kill the first generation after six months, and do that…

Here’s an interesting experiment that I don’t recommend trying at home. Take a strain of mice, and choose what age you’d like them to live to. The average lifespan for mice in captivity is around two years, so let’s say you give them six months. Kill the first generation after six months, and do that…

LEAF takes an incisive look at the popular “eternal snoozefest” view of life extension and knocks down that shaky extrapolation from elderly people’s will to live, along with several other misconceptions about boredom. LEAF “You want me to live in the beautiful Italian countryside, eat delicious Italian home cooking, and hang out at Italian beaches…

“All of this time I had been thinking about telomere maintenance in terms of the minuscule cellular molecular structures that they are, and the genes that control telomeres. When Elissa posed her question, however, I suddenly saw telomeres in a whole new light. I saw how they impacted the lives of real people.” More of…

Is a picture worth a thousand biomarkers? MouseAGE, the AI that wants to eyeball the age of rodents, thinks so. thinks so Dr. Craig Thomspon talks cancer metabolism, and fills us in on how certain nutrients may explain the connection between cancer and obesity. “The TAME Trial would cost 96% less than the cost to…

A study of centenarians finds a certain mutation of the growth hormone receptor gene is more common among men, but not women, compared to 70-year-old controls. But the modification doesn’t do what you might expect: though decreasing the amount of growth hormone absorbed, it also boosted protein expression when it was absorbed. This lead carriers to be…

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