What good is a longer life if you have to spend half of it keeping up with the news? Ditch those endlessly scrolling feeds, and instead join us every other week for a concentrated dose of the most exciting developments in the field of geroscience. Here’s the recap: Naked mole rats really do age better,…

Just getting started around here, or want to introduce someone new to the world of longevity science? This handy primer from Laura Deming (of Longevity Fund) might be just what the doctor ordered. primerLongevity Fund Ring in the new year with retrospectives of 2017 from Fight Aging! and the Life Extension Advocacy Foundation, then start…

We want you! Reason over at Fight Aging! lists nine promising approaches to rejuvenation therapy that he’d like to see in the very near future: assessment of senolytics, medical tourism, immune rejuvenation, glucosepane cross-link breaking, amyloid clearance, lysosome cleanup, telomere-centric blockades of cancer, cell therapies, and improved gene therapy. If this describes your work, consider

No one should have to read during the holidays. That’s why we made you a video! I spoke to our own James Peyer about how he got started in the longevity world, the unique challenges of bringing new anti-aging therapeutics to the public, and how his role as an investor allows him to help projects

Since the world of Alzheimer’s therapeutics hasn’t seen much practical benefit from targeting harmful proteins like amyloid-beta, maybe other approaches like targeting dysfunctional mitochondria are worth exploring in more depth. Apparently, improving mitochondrial function can decrease plaque burden and improve cognition in a mouse model. Why do cancer survivors have shorter lifespans than the rest

The immune system degrades as we age. The elderly get sick more often, take longer to recover from illness or injury, are more prone to cancer, and more prone to autoimmune issues. Why this happens is a question scientists are just beginning to answer.   Like other cells, your immune cells are subject to telomere…

All cells in your body have the same DNA, yet they express different proteins and do different things. How does that happen?  Various alterations in your cells affect the expression of genes, without altering their contents.  This is known as epigenetics. Cells of different tissue types have different epigenetic alterations that lead them to produce…

For much of the 20th century, the prevailing wisdom was that once cells were fully differentiated, their identities were crystallized eternally–a neuron was a neuron forever, and that was that. Then in 1987, something almost magical happened for the first time: with the help of a single transcription factor, a mature fibroblast was completely remade…

We can reprogram existing scar tissue into healthy organ tissue, but we didn’t know what was actually going on inside these newly revitalized cells until now. You know those articles blowing up in the popular press about how countering aging is “mathematically impossible”? Don’t get all excited–it’s just a new evolutionary theory of why aging…

The year is 1996, and you’re a doctor with a strange case on your hands. Actually, it’s not just one case–it’s an entire family with a collection of rare disorders and unrelated bodily dysfunction. Must be something genetic, right? But it doesn’t look like any of the genetic diseases you’ve seen before, because it’s going…

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