VIDEO: This animation highlights recent research by scientists at the University of Texas at Dallas who devised a way to isolate aggressive cells thought to form the root of many hard-to-treat… view more
Researchers at The University of Texas at Dallas have devised a new technique to isolate aggressive cells thought to form the root of many hard-to-treat metastasized cancers — a significant step toward developing new drugs that might target these cells.
“Our lab is interested in finding ways to prevent cancer recurrence,” said Dr. Jiyong Lee, assistant professor in the Department of Chemistry and Biochemistry in the School of Natural Sciences and Mathematics at UT Dallas. “The problem is, not all cancer cells are equal.
“There is a small population of cancer cells that is much more aggressive than others — cancer stem cells,” Lee said. “These give rise to secondary tumors, even after the primary tumor has been successfully treated. The cells are notoriously difficult to find, let alone eradicate.”
Lee and his colleagues used a two-step process to sort through a library of 40,000 chemical compounds, looking for any that would selectively bind to breast cancer stem cells, isolating them from standard breast cancer cells.
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